Resources

READ, LISTEN, OR WATCH TO LEARN MORE ABOUT HYPERCORTISOLISM

Information about type 2 diabetes (T2D) and hypercortisolism

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When to suspect hidden hypercortisolism in type 2 diabetes: a meta-analysis

Aresta C, Soranna D, Giovanelli L, et al. When to suspect hidden hypercortisolism in type 2 diabetes: a meta-analysis. Endocr Pract. 2021;27(12):1216-1224. doi:10.1016/j.eprac.2021.07.014

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Hypercortisolism in newly diagnosed type 2 diabetes: a prospective study of 384 newly diagnosed patients

Steffensen C, Dekkers OM, Lyhne J, et al. Hypercortisolism in newly diagnosed type 2 diabetes: a prospective study of 384 newly diagnosed patients. Horm Metab Res. 2019;51(1):62-68. doi:10.1055/a-0809-3647

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Diagnosis of endocrine disease: prevalence of hypercortisolism in type 2 diabetes patients: a systematic review and meta-analysis

Steffensen C, Pereira AM, Dekkers OM, Jørgensen JO. Diagnosis of endocrine disease: prevalence of hypercortisolism in type 2 diabetes patients: a systematic review and meta-analysis. Eur J Endocrinol. 2016;175(6):R247-R253. doi:10.1530/EJE-16-0434

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Information about the clinical consequences of hypercortisolism

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Increased risk of cardiometabolic comorbidities in patients with adrenal incidentalomas with and without autonomous cortisol secretion

Elhassan YS, Alahdab F, Prete A, et al. Natural history of adrenal incidentalomas with and without mild autonomous cortisol excess. Ann Intern Med. 2019;171(2):107-116.

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Cardiovascular events and mortality in patients with adrenal adenomas and excess cortisol secretion

Di Dalmazi G, Vicennati V, Garelli S, et al. Cardiovascular events and mortality in patients with adrenal incidentalomas that are either non-secreting or associated with intermediate phenotype or subclinical Cushing’s syndrome: a 15-year retrospective study. Lancet Diabetes Endocrinol. 2014;2(5):396-405. doi:10.1016/S2213-8587(13)70211-0 

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Effects of cortisol levels on mortality rates in patients with adrenal adenomas

Debono M, Bradburn M, Bull M, Harrison B, Ross RJ, Newell-Price J. Cortisol as a marker for increased mortality in patients with incidental adrenocortical adenomas. J Clin Endocrinol Metab. 2014;99(12):4462-4470. doi:10.1210/jc.2014-3007

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Increased cardiovascular disease risk in patients with hypercortisolism

Morelli V, Reimondo G, Giordano R, et al. Long-term follow-up in adrenal incidentalomas: an Italian multicenter study. J Clin Endocrinol Metab. 2014;99(3):827-834. doi:10.1210/jc.2013-3527

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Information about assessing and diagnosing hypercortisolism

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Clinical approach to evaluating incidentally discovered adrenal adenomas

Vaidya A, Hamrahian A, Bancos I, Fleseriu M, Ghayee HK. The evaluation of incidentally discovered adrenal masses. Endocr Pract. 2019;25(2):178-192. doi:10.4158/DSCR-2018-0565

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PODCASTS

Cushing’s disease and syndrome: The evolving story of hypercortisolism

In a podcast from Pituitary World News, experts discuss how the understanding of Cushing syndrome has expanded to include a variety of symptoms, disease causes, and laboratory test result ranges.

LISTEN TO PODCAST

VIDEOS

Hypothalamus-­pituitary­-adrenal (HPA) axis video thumbnail.
Hypothalamus-Pituitary-Adrenal (HPA) Axis 2:39

Learn how cortisol is controlled by the HPA axis

Treatments for patients with hypercortisolism video thumbnail.
Treatments for patients with hypercortisolism 2:44

Learn about different treatments available to patients with hypercortisolism

Tests for hypercortisolism video thumbnail.
Screening tests for hypercortisolism 2:49

Learn about the different tests used to screen hypercortisolism

EDUCATIONAL BROCHURES

CATALYST Study Results: Phase 1 PDF.

CATALYST Study Results: Phase 1

Take a look at the latest data regarding the prevalence of hypercortisolism in patients with difficult-to-control type 2 diabetes

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Increased risk of comorbidities and cardiovascular events with hypercortisolism PDF.

Increased risk of comorbidities and CV events with hypercortisolism

Take a look at a review of the Petramala et al. 2020 study

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When to suspect hidden hypercortisolism in type 2 diabetes: a meta­-analysis PDF.

When to suspect hidden hypercortisolism in type 2 diabetes: a meta-analysis

Take a look at a review of the Aresta et al. 2021 study

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Difficult­-to-­control diabetes: is cortisol at play? PDF.

Difficult-to-control diabetes: is cortisol at play?

This review captures highlights from a roundtable discussion from experts

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Dexamethasone Suppression Test (DST) Patient Tool PDF.

DST patient tool

Help patients understand how to take a 1-mg DST test and how it works

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Could it be hypercortisolism? PDF.

COULD IT BE HYPERCORTISOLISM?

Patients can review this checklist with their doctor to determine if testing for hypercortisolism is appropriate for them

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Endocrine Society Cushing's syndrome diagnosis PDF.

Endocrine Society Cushing’s syndrome diagnosis pocket guide

Look at this quick reference guide for the treatment and screening of hypercortisolism

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Understanding the spectrum of hypercortisolism PDF.

Understanding the spectrum of hypercortisolism brochure

Get a better understanding of the signs and symptoms of hypercortisolism

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