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Resources

For more about hypercortisolism, refer to the tools below, which include patient stories and the Endocrine Society’s Cushing’s Syndrome Diagnosis Pocket Guide.

Article summaries and highlights

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Increased risk of cardiometabolic comorbidities in patients with adrenal incidentalomas with and without autonomous cortisol secretion

Yasir Elhassan, Fares Alahdab, Alessandro Prete, et al. Natural history of adrenal incidentalomas with and without mild autonomous cortisol excess. Ann Intern Med. 2019;171(2):107-116.
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Cardiovascular events and mortality in patients with adrenal adenomas and excess cortisol secretion

Guido Di Dalmazi, Valentina Vicennati, Silvia Garelli, et al. Cardiovascular events and mortality in patients with adrenal incidentalomas that are either non-secreting or associated with intermediate phenotype or subclinical Cushing’s syndrome: a 15-year retrospective study. Lancet Diabetes Endocrinol. 2014;2:396-405.
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Effects of cortisol levels on mortality rates in patients with adrenal adenomas

Miguel Debono, Mike Bradburn, Matthew Bull, Barney Harrison, Richard J. Ross, John Newell-Price. Cortisol as a marker for increased mortality in patients with incidental adrenocortical adenomas. J Clin Endocrinol Metab. 2014;99(12):4462-4470.
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Increased cardiovascular disease risk in patients with hypercortisolism

Valentina Morelli, Giuseppe Reimondo, Roberta Giordano, et al. Long-term follow-up in adrenal incidentalomas: an Italian multicenter study. J Clin Endocrinol Metab. 2014;99(3):827-834.
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Clinical approach to evaluating incidentally discovered adrenal adenomas

Anand Vaidya, Amir Hamrahian, Irina Bancos, Maria Fleseriu, Hans K. Ghayee, on behalf of the AACE Pituitary, Gonad, Adrenal, and Neuroendocrine Disease State Network. The evaluation of incidentally discovered adrenal masses. Endocr Pract. 2019;25(2):178-192.

Downloadable resources

endocrine diagnosis pocket guide

Endocrine Society Cushing's Syndrome Diagnosis Pocket Guide

Understanding the Spectrum of Hypercortisolism

Understanding the Spectrum of Hypercortisolism Brochure

Patient stories

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Jenny

Age: 33

Family: Married for more than a decade with 2 young children

Career: History major and aspiring teacher

Medical History: Thyroid nodule removal surgery, medication for symptoms; considering pituitary adenoma removal surgery

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Pat

Age: 69

Family: Married for 41 years with a son and granddaughter

Career: Collegiate athletics and YMCA

Medical History: Heart attack, kidney disease

Treatment History: Medication for symptoms, heart and kidney medications, kidney removal surgery, hospitalization for fluid retention

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Charsetta

Age: 47

Career: Customer service representative for a telecommunications company

Medical History: Type 1 diabetes, type 2 diabetes, hypertension, pituitary adenomas, recurrent Cushing syndrome

Treatment History: Insulin medication, antihypertensive medication, pituitary adenoma removal surgery

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Nicole

Age: 26

Career: Client services representative for a bovine reproduction company

Medical History: Diagnosed with multiple syndromes, disorders, and diseases prior to the diagnosis of Cushing disease

Treatment History: Bilateral adrenalectomy, steroid replacement therapy